nerve growth factor pathway (ngf)
| PAG Title | nerve growth factor pathway (ngf) |
| PAG ID | WAG000217 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and proliferation of neurons. In cell culture NGF induces the formation of neurite projections and in vivo may stimulate the innervation of tissues. NGF plays a role in the repair, regeneration, and protection of neurons, and as such could serve as a therapeutic agent in neurodegenerative conditions such as Alzheimer's disease. One potential method of NGF application would be through gene therapy or through implantation of cells that have been genetically modified ex vivo. NGF has also been suggested to play a role in other physiological systems and tissues such as the immune system. |
| Species | Homo sapiens |
| nCoCo Score | 3,591 |
| Base PAG ID | WAG000217 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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